Inhibitory effects of green tea polyphenol on glucan synthesis and cellular adherence of cariogenic streptococci.

• SAKANAKA Senji

  Central Research Laboratories, Taiyo Kagaku Co., Ltd.

• SATO Tokiko

  Central Research Laboratories, Taiyo Kagaku Co., Ltd.

• KIM Mujo

  Central Research Laboratories, Taiyo Kagaku Co., Ltd.

• YAMAMOTO Takehiko

  Department of Biotechnology, Fukuyama University

抄録

Inhibitory effects of green tea poly phenols on glucan synthesis by glucosyltransferases of Streptococcus mutans MT8148 and Streptococcus sobrinus 6715DP and on sucrose-dependent adherence of the bacterial cells were examined in vitro. The glucan synthesis by the bacterial glucosyltransferase was strongly inhibited by (-)-epicatechin gallate (ECg) and (-)-epigallocatechin gallate (EGCg), the main components of the tea polyphenols. It was also demonstrated that ECg and EGCg interfered with the sucrose-dependent adherence of those bacterial cells at much smaller concentrations than those which were needed to inhibit the growth of the bacteria.

収録刊行物

• Agricultural and Biological Chemistry

  Agricultural and Biological Chemistry 54 (11), 2925-2929, 1990

  公益社団法人 日本農芸化学会

キーワード

• General Agricultural and Biological Sciences
• General Biochemistry, Genetics and Molecular Biology

詳細情報

• CRID: 1390001206463244416
• NII論文ID: 110006324670
• NII書誌ID: AA00515312
• DOI: 10.1271/bbb1961.54.2925
• COI: 1:CAS:528:DyaK3MXjvFSjsw%3D%3D
• ISSN: 18811280
• ISSN: 00021369
• ISSN: http://id.crossref.org/issn/00021369
• Web Site: https://search.jamas.or.jp/link/ui/1993149870
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可