Microbial production of 2-keto-L-gulonic acid from L-sorbose and D-sorbitol by Gluconobacter melanogenus.

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Abstract

The strain SPO1 producing 13 g of 2-keto-L-gulonic acid (2KGA) per liter was isolated as a spontaneous mutant of Gluconobacter melanogenus IFO 3293. For the enhancement of 2KGA productivity, we did further strain improvement studies of the mutant.<br> As a result, the mutant U13, producing about 60 g of 2KGA per liter from 100 g of L-sorbose per liter, was obtained. In addition, the mutant Z84, producing about 60 g of 2KGA per liter from 100 g of o-sorbitol per liter, was also obtained.<br> During the fermentation from L-sorbose and D-sorbitoI, 5 to 10 g of L-idonic acid per liter was produced as a by-product, but L-idonic acid was converted to 2KGA before the end of fermentation.

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Details 詳細情報について

  • CRID
    1390282681440546816
  • NII Article ID
    110006324922
  • NII Book ID
    AA00515312
  • DOI
    10.1271/bbb1961.54.1201
  • COI
    1:CAS:528:DyaK3cXktlyrsr4%3D
  • ISSN
    18811280
    00021369
    http://id.crossref.org/issn/00021369
  • Text Lang
    en
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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