Stimulation and inhibition of interferon-.BETA. production of human diploid fibroblasts by foodstuffs.
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- YAMADA Koji
- Department of Food Science and Technology, Kyushu University
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- MATSUMURA Kuniko
- Department of Food Science and Technology, Kyushu University
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- SUZAKI Masakazu
- Department of Food Science and Technology, Kyushu University
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- SHIRAHATA Sanetaka
- Graduate School of Genetic Resources Technology, Faculty of Agriculture, Kyushu University
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- MURAKAMI Hiroki
- Graduate School of Genetic Resources Technology, Faculty of Agriculture, Kyushu University
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We screened for foodstuffs affecting interferon-β (IFN-β) production of human foreskin diploid fibroblasts, in the presence of poly I poly C, cycloheximide, and actinomycin D. α- and β-caseins stimulated IFN-β production dose-dependently, but κ-casein inhibited it. Of the two chymosin fragments of κ-casein, glycomacropeptide was an inhibitor but p-κ-casein was not. β-lactoglobulin stimulated IFN-β production weakly, but lactoferrin inhibited it strongly. It was also shown that serum contained some factors inhibiting IFN-β induction and stimulating its production.
収録刊行物
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- Agricultural and Biological Chemistry
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Agricultural and Biological Chemistry 55 (3), 829-832, 1991
公益社団法人 日本農芸化学会
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詳細情報
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- CRID
- 1390001206465068032
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- NII論文ID
- 110006325441
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- NII書誌ID
- AA00515312
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- ISSN
- 18811280
- 00021369
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- PubMed
- 1369307
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- 本文言語コード
- en
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- データソース種別
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- JaLC
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- PubMed
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