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Abstract
Zn-proline (5 mol%) performs as a novel water-soluble and recyclable Lewis acid catalyst for the selective synthesis of 1,2-disubstituted benzimidazoles from wide range of substituted o-phenylenediamines and aldehydes in moderate to excellent isolated yields (42-92%) using water as solvent at ambient temperature.
Journal
- Chemical & pharmaceutical bulletin [List of Volumes]
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Chemical & pharmaceutical bulletin 55(8), 1254-1257, 2007-08-01 [Table of Contents]
The Pharmaceutical Society of Japan