.ALPHA.-Glucosidase Inhibitors from Millettia conraui

  • Tiabou Tchinda Alembert
    Center of Medicinal Plants Studies and Traditional Medicine (CRPMT), Institute of Medical Research and Medicinal Plants Studies (IMPM)
  • Nahar Khan Shamsun
    H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi
  • Fuendjiep Victorine
    Center of Medicinal Plants Studies and Traditional Medicine (CRPMT), Institute of Medical Research and Medicinal Plants Studies (IMPM)
  • Ngandeu François
    Department of Chemistry, University of Dschang
  • Ngono Ngane Annie
    Department of Biochemistry, University of Douala
  • Choudhary Muhammad Iqbal
    H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi

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抄録

A new geranylated isoflavone, 7-O-geranyl-6-methoxypseudobaptigenin (1) was isolated from the stem barks of Millettia conraui, along with known compounds 5-methoxydurmillone (2), conrauinone A (3), β-amyrine (4), sitosterol (5), 3-O-β-D-glucopyranosyl sitosterol (6) and n-docosanol (7). Compounds 1 and 4 showed a significant α-glucosidase inhibitory activity. The structures of the compounds were determined by analysis of their spectroscopic data.

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