集学的治療が奏効し,長期生存が得られた進行陰茎癌の1例  [in Japanese] A CASE OF LONG-TERM SURVIVAL OF ADVANCED PENILE CARCINOMA TREATED WITH COMBINATION THERAPY  [in Japanese]

Abstract

72歳,男性.近医入院中に外陰部腫瘤を指摘され,1997年12月に当科紹介となった.初診時,T4N2M0とすでに進行癌の状態であったが,THP-ADMを用いた化学療法と放射線照射の併用の後,腫瘤は縮小し,1998年4月に全除精術および両側鼠径リンパ節郭清術を施行した.摘出標本の病理診断は高分化型扁平上皮癌であったが,切除断端にcarcinoma cellは認めず,リンパ節転移も認めなかった.陰茎癌の臨床病期stageIVの予後はきわめて不良と報告されるなかで,術後8年以上健在であったという症例は本邦では未だ報告されていない.排尿は膀胱瘻管理となったが,現在も外来に定期通院中である.

A 72-year-old man with genital ulcerative tumor was introduced to our hospital in December 1997. The pathological examination revealed well differentiated squamous cell carcinoma. A diagnosis by computed tomography and magnetic resonance imaging indicated that a locally advanced penile carcinoma had infiltrated the urethra, prostate, pubic bone and there was also bilateral inguinal lymphoadenopathy. Linac irradiation (40Gy/4 weeks) combined with once-a-week administration of THP-ADM were indicated. One month after the combination therapy, the tumor size had become small enough to allow curative surgical treatment. Pathological examination revealed no positive margin. For eight years since this radical treatment, the patient has been healthy with no local recurrence and no distant metastatic lesion.

Journal

The Japanese Journal of Urology   [List of Volumes]

The Japanese Journal of Urology 98(6), 776-780, 2007-09-20  [Table of Contents]

The Japanese Urological Association

References:  18

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Codes

  • NII Article ID (NAID) :
    110006436895
  • NII NACSIS-CAT ID (NCID) :
    AN00196577
  • Text Lang :
    JPN
  • Article Type :
    NOT
  • ISSN :
    00215287
  • NDL Article ID :
    8950320
  • NDL Source Classification :
    ZS39(科学技術--医学--皮膚科学・泌尿器科学)
  • NDL Call No. :
    Z19-203
  • Databases :
    CJP  NDL  NII-ELS  Journal@rchive