Synthesis and Bioassay of Amino-pyrazolone, Amino-isoxazolone and Amino-pyrimidinone Derivatives

• Padmavathi Venkatapuram

  Department of Chemistry, Sri Venkateswara University

• Venkata Subbaiah Dandu Rangayapalle Chinna

  Department of Chemistry, Sri Venkateswara University

• Mahesh Konda

  Department of Chemistry, Sri Venkateswara University

• Radha Lakshmi Thunga

  Department of Chemistry, Sri Venkateswara University

抄録

Novel amino-pyrazolone, amino-isoxazolone and amino-pyrimidinone derivatives were prepared from ethyl 4-phenylsulfonyl-2-(2′-phenylsulfonylethyl)-2-cyanobutyrate (1), ethyl 4-arylsulfonyl-3-aryl-2-cyanobutyrate (7) and ethyl 4-arylmethylsulfonyl-3-aryl-2-cyanobutyrate (8). The lead molecules have been tested for their antimicrobial activity and antioxidant property.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 55 (12), 1704-1709, 2007

  公益社団法人 日本薬学会

キーワード

• amino-pyrazolone
• amino-isoxazolone
• amino-pyrimidinone
• antimicrobial activity
• antioxidant property

詳細情報

• CRID: 1390001204168597248
• NII論文ID: 110006532111
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.55.1704
• ISSN: 13475223
• ISSN: 00092363
• NDL書誌ID: 9273914
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I9273914
• Web Site: http://www.jstage.jst.go.jp/article/cpb/55/12/55_12_1704/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可