Fusarielin A as an Anti-angiogenic and Anti-proliferative Agent: Basic Biological Characterization

• Fujimoto Haruka

  Institute of Molecular & Cellular Biosciences, The University of Tokyo

• Aoyama Hiroshi

  Institute of Molecular & Cellular Biosciences, The University of Tokyo

• Noguchi-Yachide Tomomi

  Institute of Molecular & Cellular Biosciences, The University of Tokyo

• Hashimoto Yuichi

  Institute of Molecular & Cellular Biosciences, The University of Tokyo

• Kobayashi Hisayoshi

  Institute of Molecular & Cellular Biosciences, The University of Tokyo

抄録

Fusarielin A shows anti-angiogenic activity in the human umbilical vein endothelial cell (HUVEC) tube formation assay. Structural development studies indicated the importance of the hydroxyl groups in this molecule. A ³H-labeled derivative and a fluorescent affinity-labeling agent were prepared and used to examine the cellular distribution and biological behavior of fusarielin A.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 56 (3), 298-304, 2008

  公益社団法人 日本薬学会

キーワード

• fusarielin A
• anti-angiogenic activity
• tritium-labeling
• human umbilical vein endothelial cell
• HL-60
• binding protein

詳細情報

• CRID: 1390001204169011712
• NII論文ID: 110006622632
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.56.298
• ISSN: 13475223
• ISSN: 00092363
• NDL書誌ID: 9394454
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I9394454
• Web Site: http://www.jstage.jst.go.jp/article/cpb/56/3/56_3_298/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2008187939
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可