Secondary Metabolites from the Mycelia of the Fungus Monascus pilosus BCRC 38072

• Cheng Ming-Jen

  Bioresource Collection and Research Center (BCRC), Food Industry Research and Development Institute

• Wu Ming-Der

  Bioresource Collection and Research Center (BCRC), Food Industry Research and Development Institute

• Chen Ih-Sheng

  College of Pharmacy, Kaohsiung Medical University

• Yuan Gwo-Fang

  Bioresource Collection and Research Center (BCRC), Food Industry Research and Development Institute

抄録

Three new compounds, including two phenylacetic acid derivatives, monaspilosin (1) and monaspiloindole (2), and one pyranoindole alkaloid, monaspyranoindole (3), were isolated from the EtOAc-soluble fraction of the MeOH extract of the mycelia of Monascus pilosus BCRC 38072. Twelve known compounds were also obtained in this study. The structures were elucidated by 1D and 2D NMR spectroscopy and mass spectrometry. This is the first report of Monascus metabolites with an indole ring. All isolates were also evaluated for their scavenging properties toward the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) in TLC autographic and spectroscopic assays.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 56 (3), 394-397, 2008

  公益社団法人 日本薬学会

キーワード

• <i>Monascus pilosus</i>
• Eurotiaceae
• phenylacetic acid
• pyranoindole
• 2,2-diphenyl-1-picrylhydrazyl

詳細情報

• CRID: 1390282679145630592
• NII論文ID: 110006622650
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.56.394
• ISSN: 13475223
• ISSN: 00092363
• NDL書誌ID: 9394879
• Web Site: http://id.ndl.go.jp/bib/9394879
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I9394879
• Web Site: http://www.jstage.jst.go.jp/article/cpb/56/3/56_3_394/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可