L-テアニンによる日中眠気に対する評価の研究

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  • A STUDY OF L-THEANINE AND DAYTIME DROWSINESS

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The effects of L-theanine on daytime drowsiness were investigated using the Psychomotor Vigilance Task (PVT) as an objective evaluation and the Visual Analog Scale (VAS) as a subjective evaluation. PVT evaluates the vigilance stage and ability to perform. It measures the reaction time and considers if answers are correct. It was estimated that a decrease in the ratio of correct answers, the prolongation of reaction time, and an increase in the variance of the reaction time tended to lower the vigilance. Healthy male daytime workers were recruited for this study. Data was collected from 13 participants (36.4±4.5 years old) in the morning session and collected from 14 participants (30.8±7.1 years old) in the afternoon session. The study was randomized, double-blind, placebo controlled, cross over design. The evaluations to test drowsiness were performed from 10 AM to 11 AM and from 2 PM to 5 PM. The behavioral controls before the test were referenced with the Multiple Sleep Latency Test. As the active condition, 200 mg of L-theanine were ingested 1 hour before the test. According to PVT result, the ratio of correct answers, the reaction time, and the variance of the reaction were not affected by L-theanine. Furthermore, the VAS showed that L-theanine did not induce drowsiness, but instead, that it maintained appropriate vigilance in the test participants.

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