8 生理活性アミノアシルユラシル類(イソビラルジイン、ポリオキシン)の合成研究
書誌事項
- タイトル別名
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- 8 SYNTHETIC STUDIES OF BIOLOGICALLY ACTIVE AMINOACYLURACIL DERIVATIVES : ISOWILLARDIINE AND POLYOXINS
抄録
The present report deals with the synthesis of isowillardiine (II) and the polyoxin skeleton which have the α-aminouracil structure in common, by the four-component (aldehyde, isocyanide, amine, and organic oxyacid) condensation (Ugi reaction). This reaction permited us to synthesize the above structure (in their protected forms) in one step starting from the corresponding aldehyde. Removal of the protecting group in VIII under conditions of 9N HCl-48 hr afforded isowillardiine, whereas many attempts at complete removal of the protection to XVI is not rewarding, yet.
収録刊行物
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- 天然有機化合物討論会講演要旨集
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天然有機化合物討論会講演要旨集 20 (0), 53-58, 1976
天然有機化合物討論会実行委員会
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詳細情報 詳細情報について
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- CRID
- 1390282681051442560
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- NII論文ID
- 110006677895
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- ISSN
- 24331856
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可