58 セレチウムアルカロイドの合成研究
書誌事項
- タイトル別名
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- 58 Synthetic Studies on Sceletium Alkaloids
抄録
For the purpose of synthesizing the title alkaloids starting from 2-aryl-5,5-ethylenedioxycyclohexanone (5b or 21), alkylation of 2-arylcyclohexanone (5a) in the presence of a phase transfer catalyst was examined. Namely, 5a was treated with alkyl halides in 50% aq.NaOH and benzene in the presence of 18-crown-6 to give regioselectively 2-alkyl-2-arylcyclohexanones (6) in moderate yields. The similar reaction of 5b or 21 with allyl bromide afforded 2-allyl-2-aryl-5,5-ethylenedioxycyclohexanone (9) or (22) in 69.5 or 60% yield. By use of 9 or 22, synthesis of (±)-mesembrine (1) and (±)-dihydromaritidine (17) or (±)-joubertiamine (2) was accomplished.
収録刊行物
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- 天然有機化合物討論会講演要旨集
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天然有機化合物討論会講演要旨集 24 (0), 445-451, 1981
天然有機化合物討論会実行委員会
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詳細情報 詳細情報について
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- CRID
- 1390001206074551808
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- NII論文ID
- 110006678262
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- ISSN
- 24331856
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可