81 Polyketide型生合成反応をモデルとする多環性芳香族化合物の新合成法

• 山口 雅彦

  九工大工

• 長谷部 浩一

  九工大工

• 柴藤 啓介

  九工大工

• 中島 久隆

  九工大工

• 南 享

  九工大工

書誌事項

タイトル別名

• 81 A SYNTHESIS OF POLYOXYGENATED POLYCYCLIC AROMATIC COMPOUNDS VIA POLYKETIDES

抄録

A biomimetic synthesis of polyoxygenated polycyclic aromatic compounds via polyketides was examined. Several polyoxoalkanedioates were generated from dicarboxylic acid derivatives and methyl acetoacetate dianion. And the intra-molecular condensation of the polyketoesters gave various phenolic compounds. The Ca(OAc)_2 was found to be one of the best catalysts. The treatment of aromatic glutarates with the dianion followed by Ca(OAc)_2 afforded polyhydroxy derivatives of anthracene and naphthacene related to the natural products. The arenes were oxidized to the corresponding quinones with oxygen under basic conditions. The quinones also are aromatic glutarates, and were subjected to the further extention of the ring system.

収録刊行物

• 天然有機化合物討論会講演要旨集

  天然有機化合物討論会講演要旨集 28 (0), 627-634, 1986

  天然有機化合物討論会実行委員会

詳細情報

• CRID: 1390282681049952896
• NII論文ID: 110006678611
• DOI: 10.24496/tennenyuki.28.0_627
• ISSN: 24331856
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可