41 植物生長制御物質GA_<12>,GA_<111>およびGA_<112>の全合成(口頭発表の部)
書誌事項
- タイトル別名
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- 41 Total Syntheses of Plant Growth Regulators GA_<12>, GA_<111> and GA_<112>
抄録
The gibberellins, plant growth regulators, are divided into two groups, the larger of which is C_<19> gibberellins [gibberellic acid: GA_3 (1) is a typical representative] and most of the remaining have 20 carbons. The latter possess the ent-gibberellane carbon skeleton. GA_<12> (2), GA_<111> (3), and GA_<112> (4) belong to C_<20> gibberellins and 2 is presumed to be a common intermediate in the biosynthesis of all gibberellins. A significant array of biological activities and structural complexity have made gibberellins popular targets for total synthesis. Although GA_3 (1) is produced commercially by the large-scale fermentation of the fungus Gibberella fujikuroi, most of the C_<20> gibberellin syntheses have been achieved through many functional group manipulations, in spite of starting with tricyclic compounds or natural gibberellins. An efficient synthetic route to C_<20> gibberellins would make it possible to confirm tentative new structures and to explore their biological activities. Herein we would like to present novel synthetic routes to C_<20> by a radical cyclization, and by a combination of palladium-catalyzed cycloalkenylation reaction and reverse electron demand intramolecular Diels-Alder reaction.
収録刊行物
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- 天然有機化合物討論会講演要旨集
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天然有機化合物討論会講演要旨集 42 (0), 241-246, 2000
天然有機化合物討論会実行委員会
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- CRID
- 1390001206080251520
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- NII論文ID
- 110006681943
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- ISSN
- 24331856
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
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