Three Types of Antibiotics Produced from Rhodococcus erythropolis Strains

Search this Article

Author(s)

    • Tamura Tomohiro TAMURA TOMOHIRO
    • Research Institute of Genome-based Biofactory, National Institute of Advanced Industrial Science and Technology (AIST):laboratory of Molecular Environmental Microbiology, Graduate School of Agriculture, Hokkaido University

Abstract

A total of 15 Rhodococcus erythropolis strains were characterized as antibiotic producers and classified into three groups according to their antibiotic spectrum and growth compatibility (strains within a group did not inhibit each other's growth). Each of the antibiotic groups exhibited antibiotic activity against a taxonomically different breadth of bacteria: Group I exhibited antibiotic activity against a broad range of Gram-positives; Group II, mainly against the genus Rhodococcus and some other Gram-positives; and Group III, particularly against R. erythropolis. The antibiotic compounds of the strains belonging to Groups I and II were partially purified from liquid culture media. It was found that each group produces distinct antibiotics. In contrast to the diversity of antibiotic activity, the sequence of the 16S rRNA gene in the analyzed 1,440-nt region was found to be identical in all these 15 Rhodococcus strains. In addition to the antibiotic diversity in R. erythropolis strains, we elucidated the diversity in antibiotic-producing species of the genus Rhodococcus. Thus far, only a few antibiotic-producing strains have been reported in Rhodococcus; however, our results demonstrated that the genus comprises diverse antibiotic producers, and is a good source of new antibiotics.

Journal

References:  23

You must have a user ID to see the references.If you already have a user ID, please click "Login" to access the info.New users can click "Sign Up" to register for an user ID.

Cited by:  2

You must have a user ID to see the cited references.If you already have a user ID, please click "Login" to access the info.New users can click "Sign Up" to register for an user ID.

Codes

  • NII Article ID (NAID)
    110006684369
  • NII NACSIS-CAT ID (NCID)
    AA11173196
  • Text Lang
    ENG
  • Article Type
    Journal Article
  • ISSN
    13426311
  • NDL Article ID
    9510924
  • NDL Source Classification
    ZR5(科学技術--生物学--菌類・微生物)
  • NDL Call No.
    Z54-J644
  • Data Source
    CJP  CJPref  NDL  NII-ELS  J-STAGE 
Page Top