The Electrophysiological Properties of the Mucosal Barrier in the Injured Mouse Jejunum in Ussing Chambers

    • INAGAKI-TACHIBANA Eiko
    • Department of Nutritional Sciences, School of Nutritional Sciences, Nagoya University of Arts and Sciences
    • HAYASHI Hisayoshi
    • Laboratory of Physiology, School of Food and Nutritional Sciences, University of Shizuoka
    • SUZUKI Yuichi
    • Laboratory of Physiology, School of Food and Nutritional Sciences, University of Shizuoka

Abstract

We previously suggested in the in vitro mouse jejunum that when the primary epithelial barrier on the villi was largely disabled, a secondary mucosal barrier substitutes for the primary one. This study showed that the mucosal Ca^<2+> removal did not further deteriorate the histology but increased transmural conductance and lucifer yellow flux, and decreased forskolin-induced potential difference. It is suggested that in this injury model the postulated secondary barrier is Ca^<2+>-dependent and likely to be present on or immediately beneath the mucosal surface.

Journal

Journal of nutritional science and vitaminology   [List of Volumes]

Journal of nutritional science and vitaminology 54(3), 269-271, 2008-06  [Table of Contents]

The Vitamin Society of Japan

References:  8

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Codes

  • NII Article ID (NAID) :
    110006792031
  • NII NACSIS-CAT ID (NCID) :
    AA00703822
  • Text Lang :
    ENG
  • Article Type :
    NOT
  • ISSN :
    03014800
  • NDL Article ID :
    9544342
  • NDL Source Classification :
    ZR2(科学技術--生物学--生化学)
  • NDL Call No. :
    Z53-B484
  • DOI :
    10.3177/jnsv.54.269
  • Databases :
    CJP  NDL  NII-ELS  J-STAGE