Diabetes Mellitus Does Not Affect Jugular Bulb Oxygen Saturation in Patients Undergoing Off-Pump Coronary Artery Bypass Graft Surgery

• Oh Young Jun

  Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul

• Kim Ji Young

  Department of Anesthesiology and Pain Medicine, Gachon Medical School, Gil Medical Center, Incheon

• Shim Jae Kwang

  Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul

• Yoo Kyung Jong

  Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul

• Lee Jong Wha

  Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul

• Kwak Young Lan

  Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul

抄録

Background Diabetes mellitus (DM) is associated with the impairment of cerebral oxygenation during cardiac surgery. The aim of the present study was to investigate the effects of DM on cerebral oxygenation assessed by jugular bulb oxygen saturation (SjvO₂) in patients undergoing off-pump coronary artery bypass graft surgery (OPCAB) in a prospective controlled trial. Methods and Results Twenty-three diabetic patients with glycosylated hemoglobin above 7.0% (DM group) and 23 non-diabetic patients (control group) undergoing OPCAB with no-touch aortic technique were included. A fiberoptic oximetry catheter was inserted into the jugular bulb. The lowest SjvO₂ and the number of patients with cerebral desaturation, defined as SjvO₂ less than 50% over 5 min, were recorded during coronary grafting. Three neurocognitive tests were done before surgery and at postoperative day 2 and 7. There were no differences in SjvO₂ between the groups. Furthermore, the number of patients with cerebral desaturation and all neurocognitive test scores were similar between the 2 groups. None of the patients developed neurocognitive dysfunction. Conclusions Cerebral oxygenation in diabetic patients was similar to that of non-diabetic patients and well maintained above the critical level without resulting in clinically significant postoperative neurocognitive dysfunction during OPCAB with no-touch aortic technique. (Circ J 2008; 72: 1259 - 1264)<br>

収録刊行物

• Circulation Journal

  Circulation Journal 72 (8), 1259-1264, 2008

  一般社団法人 日本循環器学会

キーワード

• Coronary artery bypass surgery
• Diabetes mellitus
• Jugular bulb oxygen saturation
• Off-pump

詳細情報

• CRID: 1390282680081620992
• NII論文ID: 110006835725
• NII書誌ID: AA11591968
• DOI: 10.1253/circj.72.1259
• ISSN: 13474820
• ISSN: 13469843
• Web Site: http://www.jstage.jst.go.jp/article/circj/72/8/72_8_1259/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2008364263
• 本文言語コード: en
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