Two New Holostan-Type Triterpene Glycosides from the Sea Cucumber Bohadschia marmorata JAEGER

    • YUAN Weihua
    • Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University
    • YI Yanghua
    • Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University
    • TANG Haifeng
    • Department of Pharmacy, Xijing Hospital, Fourth Military Medical University
    • XUE Mei
    • Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University
    • WANG Zenglei
    • Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University
    • SUN Guoquan
    • Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University
    • ZHANG Wen
    • Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University
    • LIU Baoshu
    • Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University
    • LI Ling
    • Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University
    • SUN Peng
    • Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University

Abstract

Two new holostan-type triterpene glycosides, 17-hydroxy fuscocineroside B (1) and 25-hydroxy fuscocineroside B (2), together with a known triterpene glycoside, fuscocineroside B (3) were isolated from the sea cucumber Bohadschia marmorata JAEGER. The structures of the new triterpene glycosides were elucidated on the basis of spectroscopic analyses and chemical reactions. Compounds 1 and 3 showed considerable antifungal activities against six strains.

Journal

Chemical & pharmaceutical bulletin   [List of Volumes]

Chemical & pharmaceutical bulletin 56(8), 1207-1211, 2008-08-01  [Table of Contents]

The Pharmaceutical Society of Japan

References:  14

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Codes

  • NII Article ID (NAID) :
    110006838338
  • NII NACSIS-CAT ID (NCID) :
    AA00602100
  • Text Lang :
    ENG
  • Article Type :
    NOT
  • ISSN :
    00092363
  • NDL Article ID :
    9587404
  • NDL Source Classification :
    ZS51(科学技術--薬学) // ZP1(科学技術--化学・化学工業)
  • NDL Call No. :
    Z53-D167
  • DOI :
    10.1248/cpb.56.1207
  • Databases :
    CJP  NDL  NII-ELS  J-STAGE