Identification of a New Cytotoxic Biflavanone from Selaginella doederleinii

    • LEE Na-Youn
    • College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans University
    • MIN Hye-Young
    • College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans University
    • LEE Jun
    • College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans University:Department of Herbal Pharmaceutical Development, Korea Institute of Oriental Medicine
    • NAM Joo-Won
    • College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans University
    • LEE Yoo-Jin
    • College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans University
    • HAN Ah-Reum
    • College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans University
    • LEE Sang Kook
    • College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans University
    • SEO Eun-Kyoung
    • College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans University

Abstract

A new biflavanone, 2,2",3,3"-tetrahydrorobustaflavone 7,4',7"-trimethyl ether (1) was isolated from the whole plant of Selaginella doederleinii HIERON. (Selaginellaceae) together with the known biflavonoid, robustaflavone 7,4',7"-trimethyl ether (2) as the cytotoxic constituents against the three human cancer cell lines, HCT, NCI-H358, and K562. The structure of the new compound 1 was elucidated by spectral analysis including various 1D-and 2D-NMR experiments.

Journal

Chemical & pharmaceutical bulletin   [List of Volumes]

Chemical & pharmaceutical bulletin 56(9), 1360-1361, 2008-09-01  [Table of Contents]

The Pharmaceutical Society of Japan

References:  10

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Codes

  • NII Article ID (NAID) :
    110006878918
  • NII NACSIS-CAT ID (NCID) :
    AA00602100
  • Text Lang :
    ENG
  • Article Type :
    NOT
  • ISSN :
    00092363
  • DOI :
    10.1248/cpb.56.1360
  • Databases :
    CJP  NII-ELS  J-STAGE