Synthesis of Dibenzofurans Directly from Aryl Halides and ortho-Bromophenols via One-Pot Consecutive SNAr and Intramolecular Palladium-Catalyzed Aryl-Aryl Coupling Reactions

    • XU Hui
    • Laboratory of Pharmaceutical Synthesis, College of Sciences, Northwest A&F University
    • FAN Ling-Ling
    • Laboratory of Pharmaceutical Synthesis, College of Sciences, Northwest A&F University

Abstract

A series of dibenzofurans were efficiently and conveniently synthesized via one-pot consecutive C (sp^2)-O bond formation reaction (SNAr) in the presence of anhydrous K_2CO_3, followed by C(sp^2)-C (sp^2) bond formation reaction (intramolecular palladium-catalyzed aryl-aryl coupling reaction) between aryl halides and ortho-bromophenols. The desired dibenzofurans were obtained in 32-99% isolated yields.

Journal

Chemical & pharmaceutical bulletin   [List of Volumes]

Chemical & pharmaceutical bulletin 56(10), 1496-1498, 2008-10-01  [Table of Contents]

The Pharmaceutical Society of Japan

References:  15

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Cited by:  1

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Codes

  • NII Article ID (NAID) :
    110006936310
  • NII NACSIS-CAT ID (NCID) :
    AA00602100
  • Text Lang :
    ENG
  • Article Type :
    Journal Article
  • ISSN :
    00092363
  • NDL Article ID :
    9655218
  • NDL Source Classification :
    ZS51(科学技術--薬学) // ZP1(科学技術--化学・化学工業)
  • NDL Call No. :
    Z53-D167
  • DOI :
    10.1248/cpb.56.1496
  • Databases :
    CJP  CJPref  NDL  NII-ELS  J-STAGE