The suppressive effect of salmon muscle extracts containing anserine on lipid accumulation in rats fed with high fat diet
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- TAKAHASHI YOSHINORI
- Central Research Laboratory, NICHIRO CORPORATION
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- KAWARASAKI MASATAKA
- Central Research Laboratory, NICHIRO CORPORATION
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- HOSHINO YOSUKE
- Central Research Laboratory, NICHIRO CORPORATION
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- HONMURA AYAKO
- Central Research Laboratory, NICHIRO CORPORATION
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- ENARI HIROYUKI
- Central Research Laboratory, NICHIRO CORPORATION
Bibliographic Information
- Other Title
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- アンセリン含有サケエキスの高脂肪食飼育ラットに対する脂肪蓄積抑制効果
- アンセリン ガンユウ サケ エキス ノ コウシボウショク シイク ラット ニ タイスル シボウ チクセキ ヨクセイ コウカ
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Abstract
The anti-obesity effect of salmon muscle extracts containing anserine (SEAns) was investigated in Sprague-Dawley (SD) rats. The SEAns was orally administered to six-week-old male SD rats, and the rats were free to feed on a high fat diet for two weeks. Administration of the SEAns suppressed the increase of body weight and reduced lipid droplet of hepatic tissue, serum lipid level and the adipose tissue mass around testis and kidney. These findings suggested that not only anserine but also the other components in the SEAns were likely to have an effect. The SEAns also suppressed the accumulation of lipid in adipocytes with dose dependency. Furthermore, the SEAns was not observed to cavse genetic toxicity by Rec-assay or oral acute toxicity on rats. Thus, the SEAns suppresses lipid accumulation and could be a safe functional food material which has an anti-obesity activity.<br>
Journal
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- NIPPON SUISAN GAKKAISHI
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NIPPON SUISAN GAKKAISHI 74 (6), 1075-1081, 2008
The Japanese Society of Fisheries Science
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Details 詳細情報について
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- CRID
- 1390282681392878464
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- NII Article ID
- 110007005918
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- NII Book ID
- AN00193422
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- COI
- 1:CAS:528:DC%2BD1MXisFeqtbs%3D
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- ISSN
- 1349998X
- 00215392
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- NDL BIB ID
- 9736771
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- Text Lang
- ja
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- Data Source
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- JaLC
- IRDB
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed