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Abstract
スギ花粉症の有病率は,日本の「国民病」といえる程に高い.一般的な治療には,マスクやメガネなどを使用したスギ花粉の回避によるセルフケアと第2世代抗ヒスタミン薬や鼻噴霧用ステロイド薬を用いたメディカルケアがある.しかし,医療機関を受診せず,いわゆる健康食品を利用した「セルフメディケーション」を行っている患者も多い.その1つに,スギ花粉をカプセルに詰めたものがある.2007年2月に,そのカプセル服用後に,アナフィラキシーショックを呈した49歳,女性を経験した.この症例の特異的IgE抗体やヒスタミン遊離試験はスギ花粉に対して陽性であった.内容物に含まれる主要抗原のCryj1量は少なかったが,この製品に含まれるスギ花粉以外にアナフィラキシーショックの原因は考えられず,服用後行ったテニスによる運動誘発アナフィラキシーショックと考えるのが妥当と結論した.
The prevalence of Japanese cedar pollinosis is high to 26.5%, and it is properly remarked as "national disease" in Japan. General therapy strategies are composed of self-care by using mask or glasses to avoid antigen, and medical-care by using second-generation antihistamines or nasal corticosteroid spray. Meanwhile, there are other so-called self-medication patients who utilize health foods but do not consult to any physician. Papilla^[○!R], commercial name of one kind of those health foods, is a capsular packed with cedar pollen. In February 2007, we experienced a 49-year-old female patient who presented anaphylaxis shock after intake of Papilla^[○!R] capsular. In this case, her special-IgE antibody and histamine release test were both positive to cedar pollen. Although Cry j 1, the major allergen in the Papilla^[○!R] capsular is a small amount, the cause of anaphylaxis can not be reasoned as anything except the pollen contents in this product. In conclusion, it is appropriate to consider it exercise induce anaphylaxis shock due to playing tennis after intake of the capsular.
Journal
- Japanese Journal of Allergology [List of Volumes]
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Japanese Journal of Allergology 58(1), 39-44, 2009-01-30 [Table of Contents]
The Japanese Society of Allergology