Storage of Authentic Sample for Biological Monitoring of\nOrganic Solvents

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An external standard added the hippuric acid, m-methylhippuric acid and mandelic acid to the artificial urine and human urine were prepared for the quality control of biological monitoring.Thereafter, the specimens were kept at 25OC for 1, 2 and 4 weeks after freeze-drying, and change in concentrations during storage was examined by high performance liquid chromatography. The ratio of the concentrations of the three acids and creatinine after freeze-drying compares to that before storage was about 99 per cent or above under the storage condition at 25°C for 4 weeks.

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