Pathology: A case report of a cerebellar neuroblastoma in a p53 null mutation mouse
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- AGO Kyohei
- Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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- SHIBUTANI Makoto
- Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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- SAEGUSA Yukie
- Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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- SHIMA Tomomi
- Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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- TANIAI Eriko
- Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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- MITSUMORI Kunitoshi
- Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
書誌事項
- タイトル別名
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- A Case Report of a Cerebellar Neuroblastoma in a p53 Null Mutation Mouse
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We report a case of cerebellar neuroblastoma in a 19-week-old p53 null mutation mouse. A white and soft mass was observed at the cerebellar vermis. Histologically, the tumor consisted of solid growth of round to oval pleomorphic cells with frequent mitotic figures. While there were no typical cellular arrangements of embryonic neurogenic tumors, such as Homer-Wright rosette, perivascular pseudorosette, or streaming of neoplastic neurocytes, small populations of the neoplastic cells were immunohistochemically positive for synaptophysin, microtubule-associated protein 2, S-100 and nestin. Both glial fibrillary acidic protein and vimentin were entirely negative in the neoplastic cells. Based on the biological characteristics of neoplastic cells, this tumor was diagnosed as neuroblastoma of the cerebellar origin.<br>
収録刊行物
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- The Journal of Veterinary Medical Science
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The Journal of Veterinary Medical Science 71 (3), 345-347, 2009
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390001206430752512
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- NII論文ID
- 110007131176
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- NII書誌ID
- AA10796138
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- ISSN
- 13477439
- 09167250
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- NDL書誌ID
- 10221629
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
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- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可