Three Novel Sesquiterpene Glycosides of Sarcandra glabra

  • Hu Xiao-ru
    Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College
  • Yang Jun-shan
    Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College
  • Xu Xu-dong
    Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College

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抄録

Three new sesquiterpene glycosides, 8β,9β-epoxy-4α-hydroxy-5αH-lindan-7(11)-en-8α,12-olide-15-O-β-D-glucopyranoside (1, sarcaglaboside F), 4α-hydroxy-5α,8βH-lindan-7(11)-en-8α,12-olide-15-O-β-D-glucopyranoside (2, sarcaglaboside G), 4α-hydroxy-5α,8βH-eudesman-7(11)-en-8α,12-olide-15-O-β-D-glucopyranoside (3, sarcaglaboside H), together with five known compounds, chloranoside A (4), sarcaglaboside C (5), dihydrovomifoliol-O-β-D-glucopyranoside (6), 9-hydroxy-heterogorgiolide (7) and chloranthalactone B (8), were isolated from Sarcandra glabra THUMB. NAKAI. The structures and relative configurations of three new compounds were determined on the basis of their spectroscopic data and chemical evidence.

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