Tangle analysis of DNA unlinking by the Xer/FtsK system(Knots and soft-matter physics: Topology of polymers and related topics in physics, mathematics and biology)

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  • Tangle analysis of DNA unlinking by the Xer/FtsK system

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Abstract

The action of site-specific recombinases can be analyzed using the tangle method, where the reaction is characterized topologically by solving the corresponding tangle equations. We here analyze unlinking of DNA catenanes by the site-specific recombination system Xer/FtsK (Grainge et al., 2007). In particular we show that the key tangle involved in this reaction is rational. Therefore all solutions to the tangle equations can be computed using tangle calculus.

Journal

  • 物性研究

    物性研究 92 (1), 89-92, 2009-04-20

    物性研究刊行会

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