Veno-occlusive disease associated with a periportal edema in a child diagnosed with Wilms' tumor

• OWARI,Mitsugu

  Depertment of Pathology Nara Hospital, Kinki University school of Medicine

• KOSUMI,Takuya

  Depertment of Pathology Nara Hospital, Kinki University school of Medicine

• YONEKURA,Takeo

  Depertment of Pathology Nara Hospital, Kinki University school of Medicine

• Ohta,Yoshio

  Department of Pediatric Surgery Nara Hospital, Kinki University school of Medicine

Bibliographic Information

Other Title

• 肝内門脈周囲に著明な浮腫を呈したveno-occlusive diseaseの1例

Abstract

We experienced veno-occlusive disease of the liver (VOD) that developed ascites without jaundice. The patient was treated for a left-sided Wilms' tumor without metastasis according to the Japan Wilms Tumor Study Group (JWiTS) protocol after operation. High fever, severe abdominal distention and 16% weight gain developed on the fourth day after the second cycle of actinomycin-D. Contrast-enhanced computed tomography (CT) revealed massive ascites associated with periportal edema. The patient was diagnosed as VOD. Seven days after treatment with steroids, ascites disappeared and deterioration of liver function without jaundice developed thereafter. A follow-up CT confirmed the disappearance of the periportal edema. The patient underwent chemotherapy without actinomycin-D and survived without any recurrence of disease.

Journal

• 小児がん : 小児悪性腫瘍研究会記録

  小児がん : 小児悪性腫瘍研究会記録 46 (3), 359-363, 2009-09-25

  がんの子供を守る会

Keywords

• Veno-occulusive disease
• periportal edema
• CT
• veno-occulusive disease of the liver
• Wilms' tumor
• actinomycin-D
• ascites

Details

• CRID: 1543105995148324096
• NII Article ID: 110007359128
• NII Book ID: AN00116159
• Web Site: http://dl.ndl.go.jp/info:ndljp/pid/10755248
• Web Site: https://search.jamas.or.jp/link/ui/2009340559
• Text Lang: ja
• Data Source:
  • NDL-Digital
  • CiNii Articles