山形県で発生したShimokoshi型リケッチア感染によるつつが虫病の1例

• 大谷 勝実

  山形県衛生研究所:山形大学大学院医学系研究科公衆衛生学講座

• 金子 紀子

  山形県衛生研究所

• 青木 敏也

  山形県村山保健所

• 藤田 博己

  大原綜合病院附属大原研究所

書誌事項

タイトル別名

• A case report of Shimokoshi type Orientia tsutsugamushi from Yamagata Prefecture, Japan
• ヤマガタケン デ ハッセイ シタ Shimokoshiガタ リケッチア カンセン ニ ヨル ツツガムシビョウ ノ 1レイ

抄録

We reported a case of tsutsugamushi disease occurring in Yamagata Prefecture in Nov, 2007. A 70-year old man was admitted to the hospital for fever (38.9℃), skin rash, and an eschar on his neck. Laboratory examination of serum taken 14 days after onset of the illness showed elevated titers of antibodies against the Shimokoshi strain of Orientia tsutsugsmushi (IgG: 1:2,560; IgM: 1:5,120). The gene encoding the 56-kDa-protein specific for O. tsutsugamushi was detected by PCR from the patient's blood. Further sequence analysis of the PCR product (1,768 bpfragment including ORF region) revealed 99.4%, and 98.5% similarities to the Shimokoshi strain (Accession No: M63381) at the nucleotide and amino acid levels, respectively. Therefore, a very rare case of Shimokoshi-type tsutsugamushi disease was found in Yamagata Prefecture. Identification of the trombiculid species of vectors for this type of tsutsugamushi disease is needed in the future.

収録刊行物

• 衛生動物

  衛生動物 60 (4), 317-321, 2009

  日本衛生動物学会

キーワード

• tsutsugamushi disease
• Shimokoshi type
• 56-kDa-protein gene

詳細情報

• CRID: 1390282679918610176
• NII論文ID: 110007503663
• NII書誌ID: AN00021948
• DOI: 10.7601/mez.60.317
• ISSN: 21855609
• ISSN: 04247086
• NDL書誌ID: 10530379
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I10530379
• Web Site: https://www.jstage.jst.go.jp/article/mez/60/4/60_KJ00005928169/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2010178947
• 本文言語コード: ja
• データソース種別:
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