音韻性錯語・接近現象を認める進行性失語(神経内科学教室岩田誠教授退任記念特別号) Progressive Aphasia With Phonemic Paraphasias and Conduite d'Approche(Special Issue in Hornor of the Retirement of Professor Makoto Iwata at the Department of Neurology, Tokyo Women's Medical University)

この論文をさがす

著者

    • 永井 知代子 NAGAI Chiyoko
    • 科学技術振興機構ERATO浅田プロジェクト Asada Synergistic Intelligence Project, Exploratory Research for Advanced Technology, Japan Science and Technology Agency
    • 大橋 高志 OHASHI Takashi
    • 東京女子医科大学医学部神経内科学 Department of Neurology, Tokyo Women's Medical University, School of Medicine
    • 岩田 誠 IWATA Makoto
    • 東京女子医科大学医学部神経内科学 Department of Neurology, Tokyo Women's Medical University, School of Medicine

抄録

We reported a case of a 74-year-old, right-handed woman who had progressive aphasia for more than 2 years. Her intelligence and memory function were preserved. As for verbal symptom, her spontaneous speech was fluent, and repetitions and verbal comprehension were intact. She made phonemic errors in spontaneous speech, naming and writing, but she was almost able to correct them by conduite d'approche. She also she had acalculia and slightly executive dysfunction. Brain magnetic resonance imaging showed left, dominantly fronto-temporo-parietal atrophy, and in Tc-99m ECD single photon emission computed tomography, the uptake in the left ventral parietal lobe was reduced. We then thought that this was a case of slowly progressive aphasia proposed by Mesulam. The aphasic patterns of fluent progressive aphasia were often reported as amnesic aphasia and transcortical aphasia including word meaning (Gogi) aphasia, but this case was different from them, and thus rare. There are some cases that are first diagnosed as being slowly progressive aphasia, and later by their symptoms or by autopsy they are revealed to be Pick's disease, Alzheimer disease or corticobasal degeneration. This patient has acalculia and slight excusive dysfunction, so she might also have symptoms of Pick's disease or Alzheimer's disease.

We reported a case of a 74-year-old, right-handed woman who had progressive aphasia for more than 2 years. Her intelligence and memory function were preserved. As for verbal symptom, her spontaneous speech was fluent, and repetitions and verbal comprehension were intact. She made phonemic errors in spontaneous speech, naming and writing, but she was almost able to correct them by conduite d'approche. She also she had acalculia and slightly executive dysfunction. Brain magnetic resonance imaging showed left, dominantly fronto-temporo-parietal atrophy, and in Tc-99m ECD single photon emission computed tomography, the uptake in the left ventral parietal lobe was reduced. We then thought that this was a case of slowly progressive aphasia proposed by Mesulam. The aphasic patterns of fluent progressive aphasia were often reported as amnesic aphasia and transcortical aphasia including word meaning (Gogi) aphasia, but this case was different from them, and thus rare. There are some cases that are first diagnosed as being slowly progressive aphasia, and later by their symptoms or by autopsy they are revealed to be Pick's disease, Alzheimer disease or corticobasal degeneration. This patient has acalculia and slight excusive dysfunction, so she might also have symptoms of Pick's disease or Alzheimer's disease.

収録刊行物

  • 東京女子医科大学雑誌

    東京女子医科大学雑誌 78(臨時増刊号), E198-E202, 2008-02-25

    東京女子医科大学

各種コード

  • NII論文ID(NAID)
    110007524808
  • NII書誌ID(NCID)
    AN00161368
  • 本文言語コード
    JPN
  • 資料種別
    Journal Article
  • 雑誌種別
    大学紀要
  • ISSN
    00409022
  • NDL 記事登録ID
    9464272
  • NDL 雑誌分類
    ZS7(科学技術--医学)
  • NDL 請求記号
    Z19-400
  • データ提供元
    NDL  NII-ELS  IR 
ページトップへ