神経性食欲不振症に合併したたこつぼ型心筋症疑い例  [in Japanese] Two Cases of Anorexia Nervosa Suspected to be Complicated with Ampula Cardiomyopathy  [in Japanese]

    • 木村 寛也 KIMURA Hironari
    • 東京女子医科大学内分泌疾患総合医療センター内科 Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, School of Medicine
    • 野村 馨 NOMURA Kaoru
    • 東京女子医科大学内分泌疾患総合医療センター内科 Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, School of Medicine
    • 大和田 里奈 OHWADA Rina
    • 東京女子医科大学内分泌疾患総合医療センター内科 Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, School of Medicine
    • 堀田 眞理 HOTTA Mari
    • 東京女子医科大学内分泌疾患総合医療センター内科 Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, School of Medicine

    • 高野 加寿恵 TAKANO Kazue
    • 東京女子医科大学内分泌疾患総合医療センター内科 Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, School of Medicine

Abstract

We report two cases of anorexia nervosa (AN) complicated with ampula cardiomyopathy. Case 1, a 33-year-old female with a body mass index (BMI) of 9.61 kg/m^2 experienced transient unconsciousness induced by hypoglycemia. This episode was followed by increased plasma levels of creatine kinase (CK) and CK-MB, and an inverted T wave on ECG. The patient recovered from these changes within four weeks. Case 2, a 17-year-old female with a BMI of 8.79 kg/m^2 also developed identical abnormalities. An ultracardiogram revealed asynergy at the cardiac apex. Abnormal findings were also detected by T1 and BMIPP scintigraphies and MIBG scintigraphy. Ten days later cardiac movement at UCG had normalized. These changes were consistent with previous reports of ampula cardiomyopathy. Of the 28 AN patients admitted to our department during the last year, only the 2 cases whose BMI of less than 10 kg/m^2 developed ampula cardiomyopathy. The other 26 patients had a BMI greater than 10 kg/m^2. The pathogenesis of ampula cardiomyopathy remains unknown. This report demonstrates that the condition may occur in patients with AN, especially in those with a BMI of less than 10 kg/m^2.

We report two cases of anorexia nervosa (AN) complicated with ampula cardiomyopathy. Case 1, a 33-year-old female with a body mass index (BMI) of 9.61 kg/m^2 experienced transient unconsciousness induced by hypoglycemia. This episode was followed by increased plasma levels of creatine kinase (CK) and CK-MB, and an inverted T wave on ECG. The patient recovered from these changes within four weeks. Case 2, a 17-year-old female with a BMI of 8.79 kg/m^2 also developed identical abnormalities. An ultracardiogram revealed asynergy at the cardiac apex. Abnormal findings were also detected by T1 and BMIPP scintigraphies and MIBG scintigraphy. Ten days later cardiac movement at UCG had normalized. These changes were consistent with previous reports of ampula cardiomyopathy. Of the 28 AN patients admitted to our department during the last year, only the 2 cases whose BMI of less than 10 kg/m^2 developed ampula cardiomyopathy. The other 26 patients had a BMI greater than 10 kg/m^2. The pathogenesis of ampula cardiomyopathy remains unknown. This report demonstrates that the condition may occur in patients with AN, especially in those with a BMI of less than 10 kg/m^2.

Journal

Journal of Tokyo Women's Medical College   [List of Volumes]

Journal of Tokyo Women's Medical College 74(4), 201-207, 2004-04  [Table of Contents]

Tokyo Women's Medical University

Cited by:  1

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Codes

  • NII Article ID (NAID) :
    110007525813
  • NII NACSIS-CAT ID (NCID) :
    AN00161368
  • Text Lang :
    JPN
  • Article Type :
    Journal Article
  • ISSN :
    00409022
  • Databases :
    CJPref  NII-ELS  IR 

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