2110 MEMSデバイス上における血管増殖因子を用いた血管構造形成の誘導(要旨講演,一般セッション:マイクロナノメカトロニクス)

• 千歳 裕之

  京大

• 平丸 大介

  京大

• 三浦 岳

  京大・JST:CREST

• 鈴木 孝明

  京大・JST:CREST

• 神野 伊策

  京大

• 小寺 秀俊

  京大・JST:CREST

書誌事項

タイトル別名

• 2110 Angiogenesis induced by vascular endothelial growth factor on MEMS device

抄録

Recently, studies of positional relationships of cells are seemed to be very important for cell biology. We proposed a novel concept that self-organized vasculature integrates artificial orifices on a device by VEGF (Vascular Endothelial Growth Factor). Sucking and clamping of Alginate Calcium gel beads containing VEGF, it is able to induce angjogenesis to orifices on embedded channels. Endothelial cells have a characteristic property that they organize vasculature by themselves in collagen gel and grow along the VEGF concentration gradient. HUVEC (Human Umbilical Vein Endothelial Cells) were cultured on device for about 7 days in the collagen gel and artificial vasculature were immobilized on orifices by self-organized.

収録刊行物

• IIP情報・知能・精密機器部門講演会講演論文集

  IIP情報・知能・精密機器部門講演会講演論文集 2008 (0), 236-237, 2008

  一般社団法人 日本機械学会

キーワード

• bio MEMS
• SU-8
• self-organization
• Alginate Calcium Gel
• VEGF
• HUVEC

詳細情報

• CRID: 1390001205900653568
• NII論文ID: 110007705033
• DOI: 10.1299/jsmeiip.2008.236
• ISSN: 24243140
• Web Site: https://www.jstage.jst.go.jp/article/jsmeiip/2008/0/2008_236/_pdf
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可