13.ジベレリンシグナル伝達制御剤の探索[II] : 受容体機能阻害剤(口頭発表)

• 尹 禎敏

  東大院・農生科・応生化

• 大谷 征史

  東大院・農生科・応生化

• 増口 潔

  東大院・農生科・応生化

• Park Seung-Hyun

  東大院・農生科・応生化

• 浅見 忠男

  東大院・農生科・応生化

• 中嶋 正敏

  東大院・農生科・応生化

書誌事項

タイトル別名

• 13. Chemical screening and characterization of an inhibitor for gibberellin receptors

抄録

Direct interaction of a gibberellin receptor GID1 with a signal repressor DELLA triggers the transduction of gibberellin signal in plants. The binding of the two molecules occurs only in the presence of gibberellin. In this study, we developed a system for screening of the chemicals which inhibit the GID1-DELLA binding, based on a yeast two-hybrid system. When biologically active gibberellin exists, the yeast can grow even in the undernourished medium. By using its growth response in the co-presence of gibberellin and each examined chemical, we performed a random screening of inhibitors to the interaction between GID1 and DELLA. We found that some chemicals inhibited this binding. Then, we examined their inhibitory effects in vitro and in planta. Finally one chemical which showed inhibitory effects to both Arabidopsis and Barley, was selected.

収録刊行物

• 植物化学調節学会 研究発表記録集

  植物化学調節学会 研究発表記録集 45 (0), 30-, 2010

  一般社団法人 植物化学調節学会

詳細情報

• CRID: 1390001204422440064
• NII論文ID: 110007767113
• DOI: 10.18978/jscrpanb.45.0_30
• ISSN: 21896313
• ISSN: 09191887
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可