マイクロチャンネルを通過する赤血球の変形挙動と内部流動の二次元数値シミュレーションによる観察(流体工学,流体機械) The Observations of the Deformation Behavior and Internal Flow of the Erythrocytes Passing through a Micro Channel by a Two-Dimensional Numerical Simulation(Fluids Engineering)

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It is particularly important to know the deformation behavior of the erythrocyte passing through a micro channel (MC) like the blood capillary. In this paper, the deformation behavior of an erythrocyte passing through the pseudo MC was calculated and observed by a two-dimensional numerical simulation of blood flow. The pseudo MC wall was created by assuming that the wall was one of the fluids which had no velocity at all times. The erythrocyte's movement and deformation were calculated by using an immersed boundary method. The following results were obtained by the simulation. An erythrocyte smoothly deformed and passed through the pseudo MC. In the pseudo MC, its shape changed to bullet-like shape and its moving velocity was almost constant. In addition, a narrow layer of only blood plasma, what we call the plasma layer, was formed between pseudo MC's wall surface and the erythrocyte membrane. It was possible that the plasma layer puts the erythrocyte into fluid lubrication. On the other hand, in our previous researches the deformation behavior of the erythrocyte passing through the MC was observed by experiments. The simulation results had good agreement particularly on an erythrocyte's deformed shape and process in MC with the experimental results.

収録刊行物

  • 日本機械学会論文集 B編

    日本機械学会論文集 B編 76(772), 2111-2117, 2010

    一般社団法人 日本機械学会

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各種コード

  • NII論文ID(NAID)
    110008006796
  • NII書誌ID(NCID)
    AN00187441
  • 本文言語コード
    JPN
  • 資料種別
    ART
  • ISSN
    03875016
  • NDL 記事登録ID
    10955116
  • NDL 雑誌分類
    ZN11(科学技術--機械工学・工業)
  • NDL 請求記号
    Z16-109
  • データ提供元
    CJP書誌  NDL  NII-ELS  J-STAGE 
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