フラボノイドの生体内輸送機構(<特集>ビタミン・バイオファクターのトランスポーター[III])

• 室田 佳恵子

  徳島大学大学院ヘルスバイオサイエンス研究部食品機能学分野:(現)近畿大学理工学部生命科学科

• 河合 慶親

  徳島大学大学院ヘルスバイオサイエンス研究部食品機能学分野

• 寺尾 純二

  徳島大学大学院ヘルスバイオサイエンス研究部食品機能学分野

書誌事項

タイトル別名

• Transport Mechanism of Dietary Flavonoids and their Metabolites
• フラボノイドの生体内輸送機構
• フラボノイド ノ セイタイナイ ユソウ キコウ

抄録

Flavonoids are present in various plant foods such as vegetables, fruits and beverages. Flavonoids are known as powerful antioxidants and have attracted much attention to their potential role in the prevention of various diseases. In plant foods, most flavonoids exist as glycosides and/or acidic forms, and the type of a sugar moiety is a major determinant of the intestinal absorption. In the gastrointestinal tract, dietary flavonoids are mainly absorbed as their aglycone forms by simple diffusion, whereas there are some kind of membrane transporters that may work for cellular influx of certain flavonoids. The predominant circulating molecules after an oral consumption are conjugative metabolites because flavonoids undergo extensive intestinal and hepatic glucuronidation and sulfation. ABC transporters have been shown to serve for the cellular efflux of flavonoid metabolites. This review will summarize the current literatures regarding on the transport mechanism of dietary flavonoids and their conjugative metabolites.

収録刊行物

• ビタミン

  ビタミン 84 (12), 589-598, 2010

  公益社団法人 日本ビタミン学会

キーワード

• flavonoid
• glycoside
• transporter
• phase II metabolism
• intestine

詳細情報

• CRID: 1390001205700914432
• NII論文ID: 110008006991
• NII書誌ID: AN00207833
• DOI: 10.20632/vso.84.12_589
• ISSN: 2424080X
• ISSN: 0006386X
• NDL書誌ID: 10946815
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I10946815
• Web Site: https://search.jamas.or.jp/link/ui/2011087011
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • NDL
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可