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I have investigated the drug interaction checking technology to apply neural network. It is important to check inter-prescription because of the risk on drug interactions. There is some probles in the case of the using current system of the interaction check. The network using this study was the feed forward type of three phases, each drug ID code was coded to the binary code. The backpropagation algorith was used as learning procedure, this computer program was developed using pascal as programming language. The learning performance was utility because absolute error was about 3%.