書誌事項
- タイトル別名
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- THE POSSIBILITY OF DETECTING NATURAL SELECTION IN PIGMENTATION CANDIDATE GENES FROM HAPLOTYPE STRUCTURE AS REVEALED BY SNP ANALYSES
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Detecting natural selection would provide valuable insight into the molecular mechanisms of pathogenesis and advanced knowledge about the history of human adaptations to local environments. This study tried to detect natural selection in pigmentation candidate genes from haplotype structure as revealed by SNP analyses. We estimated the frequencies of diplotypes (combinations of the haplotypes) expected from Hardy-Weinberg equilibrium to evaluate natural selection. We also tested for correlations between the haplotypes with a high frequency and melanin content. The results indicated the possible difference of the melanin contents among the haplotypes. We suggest the possibility of natural selection to a mutation linking to the SNPs in the haplotypes. This paper also discusses future approaches to detecting natural selection in pigmentation candidate genes from haplotype structure as revealed by SNP analyses.
収録刊行物
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- 日本生理人類学会誌
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日本生理人類学会誌 16 (2), 99-102, 2011
日本生理人類学会
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詳細情報 詳細情報について
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- CRID
- 1390001204455181696
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- NII論文ID
- 110008673769
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- NII書誌ID
- AN1052804X
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- ISSN
- 24320986
- 13423215
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可