Antihypertensive Effect of Magnesium Lithospermate B, a Component of Salviae Miltiorrhizae Radix, in Spontaneously Hypertensive Rats

Abstract

The antihypertensive effect of magnesium lithospermate B isolated from Salviae Miltiorrhizae Radix was evaluated using spontaneously hypertensive rats (SHR). Oral administration of magnesium lithospermate B lowered the systolic, mean and diastolic blood pressures in SHR, in comparison with the progressive hypertension observed in untreated control animals. Urinary excretion of both kallikrein and sodium was increased significantly in rats given magnesium lithospermate B. These data suggest that magnesium lithospermate B is useful for treatment of essential hypertension.

Journal

Natural medicines   [List of Volumes]

Natural medicines 49(2), 164-167, 1995-06-20  [Table of Contents]

The Japanese Society of Pharmacognosy

References:  26

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Codes

  • NII Article ID (NAID) :
    110008731583
  • NII NACSIS-CAT ID (NCID) :
    AN10438628
  • Text Lang :
    ENG
  • Article Type :
    ART
  • ISSN :
    13403443
  • NDL Article ID :
    3633195
  • NDL Source Classification :
    SD0(薬学)
  • NDL Source Classification :
    ZS51(科学技術--薬学)
  • NDL Call No. :
    Z19-375
  • Databases :
    CJP  NDL  NII-ELS 

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