Effects of Chinese Medicinal Plant Extracts on Mutagenicity of Trp-P-1

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Abstract

Extracts of 29 traditional Chinese medicinal plants were tested for their modifying effects on the mutagenicity of 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) by the Ames assay. Aqueous extracts of Xanthium sibricum Patr. ex WIDD., Cyathula officinalis KUAN, Polygonum cuspidatum SIEB. et ZUCC, Terminalia chebula RETZ., Zanthoxylum, bungeanum Maxim., Glycyrrhiza uralensis FISCH., Hydrocotyle sibthorpioides LAM. and Polygonum bistoria L. strongly inhibited the mutagenicity of Trp-P-1. 60% EtOH extracts of G. uralensis Fisch., P. cuspidatum SIEB. et ZUCC, Aristolochia manushuriensis KOM., P. bistorta L., Lindera aggregata (SIMS) KOSTERM and Dioscorea bulbifera L. also showed significant inhibitory activities in the same assay.

Journal

Natural medicines   [List of Volumes]

Natural medicines 49(3), 329-331, 1995-09-20  [Table of Contents]

The Japanese Society of Pharmacognosy

References:  11

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Codes

  • NII Article ID (NAID) :
    110008731617
  • NII NACSIS-CAT ID (NCID) :
    AN10438628
  • Text Lang :
    ENG
  • Article Type :
    NOT
  • ISSN :
    13403443
  • NDL Article ID :
    3646072
  • NDL Source Classification :
    SD0(薬学)
  • NDL Source Classification :
    ZS51(科学技術--薬学)
  • NDL Call No. :
    Z19-375
  • Databases :
    CJP  NDL  NII-ELS