Effects of Chinese Medicinal Plant Extracts on Mutagenicity of Trp-P-1

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Abstract

Extracts of 29 traditional Chinese medicinal plants were tested for their modifying effects on the mutagenicity of 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) by the Ames assay. Aqueous extracts of Xanthium sibricum Patr. ex WIDD., Cyathula officinalis KUAN, Polygonum cuspidatum SIEB. et ZUCC, Terminalia chebula RETZ., Zanthoxylum, bungeanum Maxim., Glycyrrhiza uralensis FISCH., Hydrocotyle sibthorpioides LAM. and Polygonum bistoria L. strongly inhibited the mutagenicity of Trp-P-1. 60% EtOH extracts of G. uralensis Fisch., P. cuspidatum SIEB. et ZUCC, Aristolochia manushuriensis KOM., P. bistorta L., Lindera aggregata (SIMS) KOSTERM and Dioscorea bulbifera L. also showed significant inhibitory activities in the same assay.

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Codes

  • NII Article ID (NAID)
    110008731617
  • NII NACSIS-CAT ID (NCID)
    AN10438628
  • Text Lang
    ENG
  • Article Type
    NOT
  • ISSN
    13403443
  • NDL Article ID
    3646072
  • NDL Source Classification
    SD0(薬学)
  • NDL Source Classification
    ZS51(科学技術--薬学)
  • NDL Call No.
    Z19-375
  • Data Source
    CJP  NDL  NII-ELS 
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