In Vitro and In Vivo Studies on Anti-Lipid Peroxidation Effect of Extract from Luobuma Leaves :

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Three Luobuma extracts prepared from Apocynum venetum L. were investigated for their antioxidant activities using non-enzymatic and enzymatic oxygen free radical generation systems in vitro, and an in vivo system using animals treated with carbon tetrachloride. The results demonstrated that Luobuma leaf extract I efficiently inhibited the lipid peroxidation reaction generated either non-enzymatically or enzymatically in vitro. Spin-trapping also revealed the same ability. In the in vivo experiment, a significant decrease in thiobarbituric acid-reactive substance in serum and liver was recognized after treatment with Luobuma leaf extract III. The activities of superoxide dismutase, catalase and glutathione peroxidase were also higher in rats given Luobuma leaf extract III.

Three Luobuma extracts prepared from Apocynum venetum L. were investigated for their antioxidant activities using non-enzymatic and enzymatic oxygen free radical generation systems in vitro, and an in vivo system using animals treated with carbon tetrachloride. The results demonstrated that Luobuma leaf extract I efficiently inhibited the lipid peroxidation reaction generated either non-enzymatically or enzymatically in vitro. Spin-trapping also revealed the same ability. In the in vivo experiment, a significant decrease in thiobarbituric acid-reactive substance in serum and liver was recognized after treatment with Luobuma leaf extract III. The activities of superoxide dismutase, catalase and glutathione peroxidase were also higher in rats given Luobuma leaf extract III.

収録刊行物

  • Natural medicines = 生薬學雜誌

    Natural medicines = 生薬學雜誌 51(4), 325-330, 1997

    日本生薬学会

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各種コード

  • NII論文ID(NAID)
    110008731756
  • NII書誌ID(NCID)
    AN10438628
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    13403443
  • NDL 記事登録ID
    4315679
  • NDL 雑誌分類
    ZS51(科学技術--薬学)
  • NDL 請求記号
    Z19-375
  • データ提供元
    CJP書誌  CJP引用  NDL  NII-ELS  IR  NDL-Digital 
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