統計学的手法を用いた生薬選定法の検討 : 抗炎症作用を有する大黄の探索  [in Japanese] Studies on selection method of crude drugs by statistical analysis. : Research on Rhubarb having anti-inflamatory activity.  [in Japanese]

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Abstract

Contents of 19 components in 34 Rhubarb samples were determind by HPLC analysis, and their 5-LOX inhibitory activities were tested. It was revealed that 5-LOX inhibition activities can be estimated by the contents of 8 components (physcion, emodin-1-O-β-D-glucoside, sennoside A, catechin, (-)-epicatechin 3-O-gallate, procyanidin B-2 3,3'-di-O-gallate, lindleyin and 3,5,4'-trihydroxystilbene-4'-(6"-O-galloyl)-glucose) in Rhubarb using a muliple regression analysis. The results obtained here were further supported by phorbol ester induced ear swelling tests in mice.

Journal

Natural medicines   [List of Volumes]

Natural medicines 55(4), 159-164, 2001-08-20  [Table of Contents]

The Japanese Society of Pharmacognosy

References:  3

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Codes

  • NII Article ID (NAID) :
    110008732116
  • NII NACSIS-CAT ID (NCID) :
    AN10438628
  • Text Lang :
    JPN
  • Article Type :
    ART
  • ISSN :
    13403443
  • NDL Article ID :
    5894919
  • NDL Source Classification :
    ZS51(科学技術--薬学)
  • NDL Call No. :
    Z19-375
  • Databases :
    CJP  NDL  NII-ELS