統計学的手法を用いた生薬選定法の検討 : 抗炎症作用を有する大黄の探索  [in Japanese] Studies on selection method of crude drugs by statistical analysis. : Research on Rhubarb having anti-inflamatory activity.  [in Japanese]

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Abstract

Contents of 19 components in 34 Rhubarb samples were determind by HPLC analysis, and their 5-LOX inhibitory activities were tested. It was revealed that 5-LOX inhibition activities can be estimated by the contents of 8 components (physcion, emodin-1-O-β-D-glucoside, sennoside A, catechin, (-)-epicatechin 3-O-gallate, procyanidin B-2 3,3'-di-O-gallate, lindleyin and 3,5,4'-trihydroxystilbene-4'-(6"-O-galloyl)-glucose) in Rhubarb using a muliple regression analysis. The results obtained here were further supported by phorbol ester induced ear swelling tests in mice.

Journal

  • Natural Medicines

    Natural Medicines 55(4), 159-164, 2001-08-20

    日本生薬学会

References:  3

  • <no title>

    DARIAS V.

    I1 Farmaco 33, 460, 1978

    Cited by (1)

  • <no title>

    奥野忠一

    多変量解析法 25, 1985

    Cited by (1)

  • <no title>

    CARLSON R.

    Agents Actions s17, 197-204, 1985

    Cited by (7)

Codes

  • NII Article ID (NAID)
    110008732116
  • NII NACSIS-CAT ID (NCID)
    AN10438628
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    13403443
  • NDL Article ID
    5894919
  • NDL Source Classification
    ZS51(科学技術--薬学)
  • NDL Call No.
    Z19-375
  • Data Source
    CJP  NDL  NII-ELS  IR 
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