Morphological, chemical and molecular biological comparison among Artemisia capillaris, A. japonica and their natural hybrids

    • Minami Motoyasu Minami Motoyasu
    • Tsukuba Medicinal Plant Research Station, National Institute of Health Sciences:(Present office)Department of Environmental Biology, Chubu University
    • Hosokawa Keizo Hosokawa Keizo
    • Tsukuba Medicinal Plant Research Station, National Institute of Health Sciences:(Present office)Present address: Department of Nutritional Management, Hyogo University
    • Sakai Eiji
    • Tsukuba Medicinal Plant Research Station, National Institute of Health Sciences:(Present office)Herbal Garden, Gifu Pharmaceutical University

    • Satake Motoyoshi
    • National Institute of Health Sciences:(Present office)Japan Pharmacist Education Center
    • Kondo Seizo
    • Central Research Laboratory, Kotaro Pharmaceutical Co., LTD.
    • Oka Kenji
    • Central Research Laboratory, Kotaro Pharmaceutical Co., LTD.
    • Koga-Ban Yasunori
    • Department of Biotechnology, National Institute of Agrobiological Resources

    • Kayano Toshiaki
    • Department of Biotechnology, National Institute of Agrobiological Resources
    • Tanaka Hiroshi
    • Department of Biotechnology, National Institute of Agrobiological Resources
    • Shibata Toshiro
    • Tsukuba Medicinal Plant Research Station, National Institute of Health Sciences:(Present office)Hokkaido Experimental Station for Medicinal Plants, National Institute of Health Sciences

Abstract

The heads of Artemisia capillaris have been used for medicinal purposes, as their choleretic effect of capillarisin (CAP) and 6,7-dimethylesculetin (DME) are known. However, hybrid plants between A. capillaris and A. japonica are often found in the crude drugs sold in the Japanese market, therefore observation of flowering dates, the ten morphological characteristics of flower heads, and CAP and DME contents, as well as RAPD (Random Amplified Polymorphic DNA) analysis were carried out for A. capillaris, A. japonica and their natural hybrid plants grown in the flood plain of the Sho-river, Takaoka, Toyama, Japan. Further, the pharmaceutical status of flower heads derived from the hybrid plants was discussed. The results showed that hybrid plants were similar to A. japonica, and when flower heads from the hybrid plants were mixed in crude drugs, the quality of the crude drug could decline because of traces of CAP and DME. Flower heads of hybrid plants could be detected with certainly by the presence of secretory sacs on corolla lobes of disk flowers and lower content of CAP and DME and removed.

Journal

Natural medicines   [List of Volumes]

Natural medicines 57(1), 1-6, 2003-02-20  [Table of Contents]

The Japanese Society of Pharmacognosy

References:  17

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Cited by:  1

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Codes

  • NII Article ID (NAID) :
    110008732226
  • NII NACSIS-CAT ID (NCID) :
    AN10438628
  • Text Lang :
    ENG
  • Article Type :
    Journal Article
  • ISSN :
    13403443
  • NDL Article ID :
    6489425
  • NDL Source Classification :
    ZS51(科学技術--薬学)
  • NDL Call No. :
    Z19-375
  • Databases :
    CJP  CJPref  NDL  NII-ELS 

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