P-21 ポリ乳酸の分解生成物の解析(溶出・滅菌・消毒・毒性,一般講演(ポスター発表),第58回日本歯科理工学会学術講演会)  [in Japanese] P-21 Analysis of degradabed products of poly (lactic acid)  [in Japanese]

Poly lactic acid is well-known to superior biodegradable material and has been interested for many applications such as extraction-tree surgical materials. However, the biodegradation induces acid products which cause pH decrease and then the decrease may lead to inflammation in local area of diseased area. In this study, we investigated hydrolysis behaviors of three types of poly lactic acid and compared the influence of their component. The hydrolysis behavior in PBS depended on their polymerization degrees and was accelerated by containing of copolymerized glycolic acid.