A Case of Pseudomembranous Aspergillus Tracheobronchitis in an Asthma Patient Receiving Inhaled Corticosteroid Therapy

DOI 参考文献12件
  • Nagashima Osamu
    Department of Respiratory Medicine, Juntendo Tokyo Koto Geriatric Medical Center
  • Iwase Akihiko
    Department of Respiratory Medicine, Juntendo Tokyo Koto Geriatric Medical Center
  • Yae Toshifumi
    Department of Respiratory Medicine, Juntendo Tokyo Koto Geriatric Medical Center
  • Kadoya Kotaro
    Department of Respiratory Medicine, Juntendo University School of Medicine
  • Ishimori Ayako
    Department of Respiratory Medicine, Juntendo University School of Medicine
  • Kuriyama Sachiko
    Department of Respiratory Medicine, Juntendo University School of Medicine
  • Koyama Ryo
    Department of Respiratory Medicine, Juntendo University School of Medicine
  • Homma Noriyuki
    Department of Respiratory Medicine, Juntendo University School of Medicine
  • Ienaga Hiroki
    Department of Respiratory Medicine, Koshigaya Municipal Hospital
  • Takahashi Kazuhisa
    Department of Respiratory Medicine, Juntendo University School of Medicine

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抄録

Background. Pseudomembranous Aspergillus tracheobronchitis, which shows striking findings in the bronchi, is a rare form of pulmonary aspergillosis. Case. We describe a case of pseudomembranous Aspergillus tracheobronchitis in an asthma patient who was receiving inhaled fluticasone propionate therapy. Bronchofibroscopy revealed a characteristic white mucus layer throughout the trachea and bronchi. Histological examination of a biopsy specimen showed numerous branched hyphae suggestive of Aspergillus in the mucosa. Pseudomembranous Aspergillus tracheobronchitis is a rare disease that usually occurs in immunocompromised patients. Conclusion. We believe that both asthmatic inflammation in the airway and inhaled corticosteroid therapy might have contributed to the development of pseudomembranous Aspergillus tracheobronchitis.

収録刊行物

  • 気管支学

    気管支学 34 (1), 71-73, 2012

    特定非営利活動法人 日本呼吸器内視鏡学会

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