P-26 アパタイトナノ粒子安定化エマルションを用いた細胞担体の開発(生体親和材料,一般講演(ポスター発表),第59回日本歯科理工学会学術講演会)  [in Japanese] P-26 Fabrication of hybrid microsphere by Pickering emulsion method and its application for cell carrier  [in Japanese]

There are strong needs for synthesis of biodegradable polymer in a form of microsphere, because they have found their applications as soft tissue fillers, injectable scaffolds and cell carriers for tissue engineering. Although biodegradable polymer found various applications, there are disadvantages including low cell adhesion due to its hydrophobic surface character. In this study, hydroxyapatite (HAp)-coated biodegradable polymer microsphere was successfully prepared from a Pickering-type emulsion stabilized with HAp nanocrystals without any molecular surfactants. The microspheres showed cell adhesiveness and should be useful for a variety of biomedical applications including implant materials and cell carriers.