下顎骨におけるアパタイト配向性の支配因子の解明

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タイトル別名
  • Study on understanding parameters for controlling degree of biological apatite in mandible

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Mandible, which is formed through intramembranous ossification process, has a well-organized nano-structure comprising preferentially-aligned collagen/biological apatite (BAp) and has a role to bear complicated mechanical stress mainly based on biting. The present study is aiming at clarifying the correlation between the preferential alignment of collagen/BAp and mechanical properties of mandible by using a microbeam X-ray diffractometer using some specific animal models: controlled biting stress, bone metabolism, nutrient disturbance and primary osteoporosis. The present study will provide a direction for designing novel dental implant from a viewpoint of bone microstructure and mechanical function.

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