Individual difference of promoter methylation patterns in human brain tissue Individual difference of promoter methylation patterns in human brain tissue

Promoter methylation is an important factor for gene expression regulation. Especially, it can control target gene regulation semipermanently. Thus, for example, it is used for tissue specific gene expression regulation. Recently, brain tissue promoter methylation patterns turn out to be more personalized than those in other tissues. In this paper, we try finding which genes are specifically methylated among individuals.

Promoter methylation is an important factor for gene expression regulation. Especially, it can control target gene regulation semipermanently. Thus, for example, it is used for tissue specific gene expression regulation. Recently, brain tissue promoter methylation patterns turn out to be more personalized than those in other tissues. In this paper, we try finding which genes are specifically methylated among individuals.