Determination of the Ca<sup>2+</sup> Levels and pH Conditions that Inhibit the Growth of <i>Porphyromonas gingivalis</i> and Suppress the Demineralization of Tooth Enamel
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- SUZUKI Daisuke
- Institute of Health Sciences, Ezaki Glico Co. Ltd.
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- YOSHIMATSU Daisuke
- Institute of Health Sciences, Ezaki Glico Co. Ltd.
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- KAMASAKA Hiroshi
- Institute of Health Sciences, Ezaki Glico Co. Ltd.
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- KURIKI Takashi
- Institute of Health Sciences, Ezaki Glico Co. Ltd.
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- MIYAZAKI Hideo
- Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Sciences, Niigata University
Bibliographic Information
- Other Title
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- 歯エナメル質の脱灰を抑制し<i>Porphyromonas gingivalis</i>の生育を抑制するpHとカルシウム濃度の探索
- 歯エナメル質の脱灰を抑制しPorphyromonas gingivalisの生育を抑制するpHとカルシウム濃度の探索
- ハ エナメルシツ ノ ダツカイ オ ヨクセイ シ Porphyromonas gingivalis ノ セイイク オ ヨクセイ スル pH ト カルシウム ノウド ノ タンサク
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Abstract
The aim of this study was to determine the Ca2+ levels and pH conditions in saliva that inhibit the generation of volatile sulfur compounds (VSC) by periodontal pathogens, while also suppressing the demineralization of tooth enamel. As causative agents of oral malodor, VSC are generated by the metabolic activity of periodontal pathogens. It is possible that this metabolic activity could be inhibited under acidic conditions, although it carries the risk of enamel erosion. However, the presence of Ca2+ can prevent the demineralization of tooth enamel under acidic conditions. Therefore, we investigated the growth of Porphyromonas gingivalis in a pH range of 7.0-3.5, and the levels of Ca2+ that prevent the demineralization of tooth enamel in this pH range. Our results enabled us to determine the optimal conditions that inhibit the generation of VSC without demineralizing the tooth enamel by the consumption of food containing calcium and organic acids.
Journal
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- JOURNAL OF DENTAL HEALTH
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JOURNAL OF DENTAL HEALTH 62 (4), 397-402, 2012
Japanese Society for Oral Health
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Details 詳細情報について
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- CRID
- 1390282679979347840
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- NII Article ID
- 110009489303
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- NII Book ID
- AN00081407
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- ISSN
- 21897379
- 00232831
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- NDL BIB ID
- 023925183
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- CiNii Articles
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- Abstract License Flag
- Disallowed