Clinicopathologic study of 186 odontogenic tumors at Osaka Dental University Hospital over 15 years

  • Fukuda Aoi
    First Department of Oral and Maxillofacial Surgery, Osaka Dental University
  • Tsuji Kaname
    First Department of Oral and Maxillofacial Surgery, Osaka Dental University
  • Hayashi Teruyoshi
    First Department of Oral and Maxillofacial Surgery, Osaka Dental University
  • Watanabe Shinya
    First Department of Oral and Maxillofacial Surgery, Osaka Dental University
  • Himejima Akio
    First Department of Oral and Maxillofacial Surgery, Osaka Dental University
  • Kono Takako
    First Department of Oral and Maxillofacial Surgery, Osaka Dental University
  • Matsushima Yuki
    First Department of Oral and Maxillofacial Surgery, Osaka Dental University
  • Sano Toshiya
    First Department of Oral and Maxillofacial Surgery, Osaka Dental University
  • Yamada Koji
    First Department of Oral and Maxillofacial Surgery, Osaka Dental University
  • Matsumoto Kazuhiro
    First Department of Oral and Maxillofacial Surgery, Osaka Dental University
  • Yoshida Hiroaki
    First Department of Oral and Maxillofacial Surgery, Osaka Dental University
  • Iseki Tomio
    First Department of Oral and Maxillofacial Surgery, Osaka Dental University
  • Morita Shosuke
    First Department of Oral and Maxillofacial Surgery, Osaka Dental University

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Histopathological records of the First Department of Oral and Maxillofacial Surgery in Osaka Dental University Hospital were reviewed retrospectively for all odontogenic tumors of the oral cavity and the jaws seen from January 1996 to December 2010. The 186 lesions were all primary cases and classified based on the 2005 WHO odontogenic tumor classification. None of the tumors was malignant. The keratocystic odontogenic tumor (KCOT) (73 cases, 39%) was the most frequent type, followed by ameloblastoma (AME) (49 cases, 26%), odontoma (OD) (41 cases, 22%), cementoblastoma (CB) (6 cases, 3%) and odontogenic myxoma (OM) (5 cases, 3%). The male to female ratio for the tumors was 1.5 :1. The average age of the patients was 37 years, with a range from 3 to 82 years. There was a peak in the third decade with 37 cases (20%). The maxilla to mandible ratio was 1 : 2.8. The anterior was the most frequent area in the maxilla, while the posterior region was more common in the mandible. Enucleation and curettage (ENC) was the most frequent treatment (67 cases, 39%) followed by enucleation (ENU) (62 cases, 36%). The next most frequent treatment was marsupialization followed by enucleation and curettage (MAR) (30 cases, 17%). Many cases were treated by conservative treatment. There was recurrence in 4 cases of ENC, 6 cases of MAR and one case of marginal resection of the mandible.

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