A Case of Primary Lymphoplasmacytic Lymphoma Limited to the Paratracheal Mediastinum

DOI Web Site Web Site PubMed 12 References
  • NOGUCHI Shingo
    Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan
  • YATERA Kazuhiro
    Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan
  • JINBO Mitsutaka
    Saiseikai Yamaguchi General Hospital
  • FUKUDA Youko
    Saiseikai Yamaguchi General Hospital
  • YAMASAKI Kei
    Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan
  • NAGATA Shuya
    Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan
  • KAWANAMI Toshinori
    Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan
  • ISHIMOTO Hiroshi
    Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan
  • MURAKI Kazuhiko
    Saiseikai Yamaguchi General Hospital
  • ONO Shiro
    Saiseikai Yamaguchi General Hospital
  • KAWANO Hiroo
    Department of Pathology, Yamaguchi University Graduate School of Medicine
  • WAKITA Yukio
    Saiseikai Yamaguchi General Hospital
  • MUKAE Hiroshi
    Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan

Bibliographic Information

Other Title
  • 気管周囲に限局した縦隔原発リンパ形質細胞性リンパ腫の1例
  • 症例報告 気管周囲に限局した縦隔原発リンパ形質細胞性リンパ腫の1例
  • ショウレイ ホウコク キカン シュウイ ニ ゲンキョク シタ ジュウカク ゲンパツ リンパ ケイシツ サイボウセイ リンパシュ ノ 1レイ

Search this article

Abstract

A 54 year old Japanese man was introduced to Saiseikai General hospital for an evaluation of an abnormal chest X-ray film. Abnormal soft tissue area was observed in the mediastinum surrounding anterior area of the trachea on chest CT. Because the mediastinal tumor showed slow enlargement after temporal decrease and surgical resection of the tumor was performed 3 years after the first visit. Pathologically, diffuse proliferation of oval-shaped plasmacytic or small lymphocytic cells with eccentrically-located nuclei with rough chromatin were observed in the tumor. Immunohistochemically, these cells were positive for CD20, weakly positive for IgM, negative for CD3, CD5, CD10, suggesting lymphoplasmacytic lymphoma (LPL). The patient was treated with rituximab after the surgical treatment, and showed no exacerbation for 3.5 years after surgery. LPL localized to the paratracheal mediastinum is rare, and a surgical approach is important for prompt and proper diagnosis.

Journal

  • Journal of UOEH

    Journal of UOEH 35 (3), 213-218, 2013-09-01

    The University of Occupational and Environmental Health, Japan

References(12)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top