P-27 歯および歯科材料に対する表面改質に関する効果 : 新規抗菌性シランカップリング剤(印象材・臨床応用,一般講演(ポスター発表),第62回日本歯科理工学会学術講演会)

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  • P-27 Surface modification effect of teeth and dental materials : Antimicrobial effect of a novel silane coupling agent

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We have synthesized a silane coupling agent having a quaternary ammonium salt group (N-allyl-N-decyl-N-methyl-N-trimethoxysilylpropylammonium iodide, 10-I) with the aim of providing antimicrobial properties to the surface of teeth and dental materials. In order to evaluate the antibacterial activity of 10-I, we conducted a dental plaque microcosm model (polymicrobial biofilm), which is a laboratory model cultured with human stimulated whole saliva. The CFU of the modified cover glass group showed a marked reduction, that was approximately 20% of the unmodified control group.

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